Last Updated: 26 Ocak 2026
Lipolytic Mesotherapy

If you are losing weight with diet and exercise but still cannot get rid of stubborn localized fat, you may consider Lipolytic Mesotherapy. This procedure has become increasingly popular because it can support regional slimming and help create a more balanced, fit-looking body silhouette. One of the biggest advantages is that lipolytic mesotherapy is not a surgical operation-it is a non-surgical body contouring treatment.

For individuals who want to reduce local fat deposits without surgery, Lipolytic Mesotherapy can be an ideal option. It is performed by injecting special active ingredients and medical solutions directly into the targeted body area where slimming is desired. There are no incisions, so there is no scarring. After the treatment, slimming gradually begins in the treated area, helping improve the appearance of spot reduction and body shaping.

Lipolytic mesotherapy has been used internationally for more than a decade and is considered a safe method when applied to suitable candidates. If the patient's fat tissue structure is appropriate, results may appear similar to liposuction-like contouring, but achieved through a more natural and minimally invasive approach.

In many protocols, ingredients such as phosphatidylcholine and deoxycholate are used. These substances have been tested and are widely used in aesthetic medicine, supporting a safe and controlled treatment process when performed by an experienced physician.

Which Areas Can Lipolytic Mesotherapy Be Applied To?

Lipolytic Mesotherapy is commonly applied to body areas where fat storage tends to be more noticeable. Most people think of the abdomen or hips first; however, this treatment can be used for several different regions.

Common treatment areas include:

  • Abdomen
  • Upper stomach area
  • Buttocks
  • Upper buttocks
  • Waistline
  • Love handles (right and left sides of the waist)
  • Hips
  • Legs
  • Inner knees
  • Areas visible above underwear lines
  • Arms
  • Under the chin (double chin)

Because fat accumulation may be more persistent in these zones, many patients choose fat dissolving injections (lipolytic mesotherapy) to improve contours and achieve a more refined appearance.

How Does Lipolytic Mesotherapy Work?

The mechanism of Lipolytic Mesotherapy mainly depends on the injected active substances. These agents can increase the permeability of the fat cell membrane, allowing fat content to be released more easily from the cell. As a result, fat cells gradually reduce in size and undergo structural changes.

In simple terms, this method can support the breakdown of fat cells and may help accelerate the body's natural slimming process.

It is important not to confuse Lipolytic Mesotherapy with liposuction. In liposuction, fat cells are physically removed from the body through a surgical technique. Lipolytic Mesotherapy, on the other hand, works through a non-surgical and more natural process, aiming to break down fat cells without opening holes in the skin or extracting fat externally.

The main goal is to support fat cell reduction and improve the body contour in targeted areas.

How Many Sessions Are Needed?

Lipolytic Mesotherapy is often planned as approximately 8 sessions, although the total number may vary based on individual factors. Stubborn fat deposits or more advanced fat accumulation may require additional sessions.

The level of fat accumulation is one of the main factors affecting the number of sessions. Patients with minimal localized fat will not need the same number of sessions as those with more noticeable fat deposits.

After each session, the response to treatment is evaluated, and the total session number is adjusted accordingly. For safe application and optimal results, the interval between two sessions should generally be at least one week. In some patients, intervals may be planned as 15 days or even one month, depending on individual needs and response.

Is Lipolytic Mesotherapy Painful?

Many patients worry about pain when considering localized fat treatments. In most cases, Lipolytic Mesotherapy is considered a comfortable and minimally painful procedure. This is also why anesthesia is usually not necessary.

Patients typically feel only mild injection discomfort. Since very fine needles are used, many people report that the sensation during injections is minimal and tolerable-and this can vary based on personal pain threshold.

Procedure Process

Naturally, patients who have never had this treatment before often want to know what the process looks like. Below is a clear overview of the lipolytic mesotherapy procedure, including answers to the most frequently asked questions.

  • Before starting fat dissolving injections, the treatment must be planned in detail.
  • During a simple clinical assessment, the targeted body area is examined and the required amount of medical solution is calculated based on fat tissue condition and the slimming goal.
  • The procedure then begins, using injectors with very fine needles for a precise and comfortable application.
  • The prepared solution is injected into the fatty tissue at 1-2 cm intervals, ensuring an even distribution across the treatment area.
  • The only sensation usually felt is mild injection discomfort, and it typically lasts just a few seconds.
  • Since the procedure is not considered painful, local anesthesia is generally not necessary.
  • Depending on the desired result and the patient's response, the next session is scheduled 1 week, 15 days, or 1 month after the first treatment.
  • Immediately after the session, patients can return to daily activities-Lipolytic Mesotherapy is a true no-downtime body contouring treatment.
  • The procedure does not prevent working, and most patients can return to work the same day.

After the Procedure

Lipolytic Mesotherapy does not involve a difficult recovery period. Since it is a non-surgical localized fat reduction treatment, there is usually no need for clinical rest or staying at home. Here are the key points patients should know after the procedure:

  • This treatment does not require a special preparation period, and there is generally no need for rest after the session.
  • Because the procedure is not painful, anesthesia is typically not used.
  • As a result, side effects related to anesthesia-such as headache, nausea, or stomach discomfort-are usually not experienced.
  • After the injections, very mild redness may appear in the treated areas.
  • Depending on the patient's skin sensitivity, this redness typically disappears spontaneously within 1-2 days.
  • When the slimming effect becomes noticeable may vary depending on the treated body area, tissue structure, metabolism, and individual response.

If you are struggling with localized fat deposits despite diet and exercise, you may benefit from Lipolytic Mesotherapy (fat dissolving injections). To get more information or request an appointment in Tekirdag near Istanbul, feel free to contact our clinic.